The proximal origin of SARS-CoV-2- Nature Medicine
The genomic features described here may explain in part the infectiousness and transmissibility of SARS-CoV-2 in humans.
Although the evidence shows that SARSCoV-2 is not a purposefully manipulated virus, it is currently impossible to prove or disprove the other theories of its origin described here. However, since we observed all notable SARS-CoV-2 features, including the optimized RBD and polybasic cleavage site, in related coronaviruses in nature, we do not believe that any type of laboratorybased scenario is plausible.
PHAGElogist 