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https://qeen-bio.com Qeen Biotechnologies is a global Center of Excellence in biomanufacturing non-traditional therapeutics. We provide services to develop and produce GMP and non-GMP bacteriophages and related delivery systems for the…

Some interesting discoveries on anti-defence systems; Diverse anti-defence systems are encoded in the leading region of plasmids Two defence systems eliminate plasmids from seventh pandemic Vibrio cholerae An antiplasmid system drives…

MVP: a modular viromics pipeline to identify, filter, cluster, annotate, and bin viruses from metagenomes https://journals.asm.org/doi/epub/10.1128/msystems.00888-24 The significance of our work lies in the development of Modular Viromics Pipeline (MVP),…

In a new study, the authors showed "Phage-based biocontrol of Porphyromonas gingivalis through indirect targeting" https://journals.asm.org/doi/abs/10.1128/aem.00951-24 IMPORTANCE Lytic phages are valuable agents for targeted elimination of bacteria in diverse applications. Nevertheless, lytic…

A new preprint article "Prophages are Infrequently Associated With Antibiotic Resistance in Pseudomonas aeruginosa Clinical Isolates" shows that prophages are not involved in the transmission of antibiotic resistance genes at…

https://www.ncbi.nlm.nih.gov/nuccore/AY288927.2 Based on our latest results, the genome annotation of one of the famous podo-phage Salmonella phage SP6 has been modified. The modified genome has identified lysis genes; holin, endolysin…

Resistance to antibiotics has led to one million worldwide deaths each year since 1990, for a total of 36 million. It is expected to cause more than 39 million more fatalities…

Read here: https://www.nature.com/articles/s41587-024-02392-z In the new study, Fishman et al. introduce a phage genome engineering system that improves these methods. Their method can produce modifications at multiple sites in a…

Title: "Safety and Tolerability of ShigActive™, a Shigella spp. Targeting Bacteriophage Preparation, in a Phase 1 Randomized, Double-Blind, Controlled Clinical Trial" https://www.mdpi.com/2079-6382/13/9/858 Bacterial diseases of the GI tract are a major global…

As antibiotic resistance becomes an increasingly serious threat to our health, the scientific and medical communities are searching for new medicines to fight infections. Researchers at Gladstone Institutes have just…