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COVID-19 has rightfully dominated infectious disease news since 2020. However, that doesn’t mean other infectious diseases took a break. In fact, U.S. rates of infection by gonorrhea have risen during the…

“Phage Therapy” Market Insights | No of Pages120| By Application [Animal Health, Aquaculture, Agriculture, Food Industry, Human Health, Others], By Type [DsDNA Bacteriophage, ssDNA Bacteriophage, ssRNA Bacteriophage, Others]. The Phage…

In vitro and in vivo evaluation of the biofilm-degrading Pseudomonasphage Motto, as a candidate for phage therapy Prasanth Manohar, Belinda Loh, Dann Turner, Tamizhselvi Ramasamy, Marimuthu Mathankumar, Namasivayam Elangovan, Ramesh Nachimuthu, Sebastian Leptihn https://www.biorxiv.org/content/10.1101/2022.10.12.512010v1 Abstract Infections caused by Pseudomonas aeruginosa are becoming increasingly difficult to treat due to the emergence…

Complete Genome Sequence of Pseudomonas Phage Motto Authors: Prasanth Manohar, Archana Loganathan, Ramesh Nachimuthu, Belinda Loh, Long Ma, Dann Turner, Sebastian Leptihn ABSTRACT We describe the complete genome sequence of bacteriophage Motto, which infects clinical strains of Pseudomonas aeruginosa. Motto is a T1-like siphovirus related to members…

In a lung transplant recipient, phage therapy was associated with a T follicular helper cell response and production of neutralizing antibody. Phage therapy with bacteriophages (viruses that infect bacteria) has…

Enrollment has begun in an early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis (CF) who carry Pseudomonas aeruginosa (P. aeruginosa) in their lungs. The trial is evaluating whether…

Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosainfection to allow liver transplantation in a toddler Nature Communications volume 13, Article number: 5725 (2022) Read here: https://www.nature.com/articles/s41467-022-33294-w

Modification of the immune response by bacteriophages alters methicillin-resistant Staphylococcus aureus infection Scientific Reports volume 12, Article number: 15656 (2022)  Abstract: There is an urgent need to develop phage therapies for multidrug-resistant bacterial infections. However, although bacteria…

Development of host immune response to bacteriophage in a lung transplant recipient on adjunctive phage therapy for a multidrug resistant pneumonia 10.1093/infdis/jiac368 Abstract Bacteriophage therapy is the use of viruses…

Widespread stop-codon recoding in bacteriophages may regulate translation of lytic genes Nature Microbiology volume 7, pages 918–927 (2022) https://www.nature.com/articles/s41564-022-01128-6 Abstract: Bacteriophages (phages) are obligate parasites that use host bacterial translation machinery to produce viral…