Dr. Prasanth Manohar, Ph.D., – Page 33 – PHAGElogist

NIH awards $2.5 million for Bacteriophage therapy

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded $2.5 million in grants to 12 institutes around the world to support…

Phage therapy on secondary Acinetobacter baumannii infection in COVID-19 patients

In this study, the authors describe the first therapeutic use of phages for the secondarybacterial infections in COVID-19 patients and the first clinical application of NEPT strategy to preview bacterial…

Mutations in metabolic genes can cause antibiotic resistance

A recent study in Science reveals a novel avenue by which genetic changes make bacteria resistant to drugs: mutations in genes involved in cellular metabolism, including some that convert food into energy. “The genes…

Bacteriophage uptake by mammalian cells

A very interesting study published in iScience titled "Bacteriophage uptake by mammalian cell layers represents a potential sink that may impact phage therapy". Source: https://www.cell.com/iscience/fulltext/S2589-0042(21)00255-8 Highlights Live-cell imaging showed that…

Interaction of bacteriophages with mammalian cells

Natural bacteriophages (present in the microbiome) and those applied as therapeutic agents may interact with mammalian cells and tissues. Adhesion interactions may define bacteriophage pharmacokinetics and resulting efficiency of bacteriophage…

Phage Therapy Successful in Mice, but Resistance Looms

Since just before the turn of the 20th century, bacteriophage’s antibacterial activity was detected in the waters of the Ganges and Yamuna rivers. English bacteriologist Ernest Hankin had written about the…

BiomX Inc. – Know about the phage company

BiomX Inc.: Clinical Stage Phage Therapeutics Company Looks Promising Summary BiomX is a clinical-stage microbiome company using its novel BOLT phage therapy platform to develop customized phage therapies to treat…

Antimicrobial Resistance Is a Serious Threat To Public Health in India

Antimicrobial resistance (AMR), brewing unnoticeably for the past couple of decades, has now evolved into a potential public-health emergency on the cusp of threatening our medical fraternity in the near…

Engineered viruses to fight the antibiotic-resistant bacteria

As the world fights the SARS-CoV-2 virus causing the COVID-19 pandemic, another group of dangerous pathogens looms in the background. The threat of antibiotic-resistant bacteria has been growing for years and appears to…

Public Awareness: Calling phage researchers

With all the latest improvements in the bacteriophage research, there is a better understanding about the biology of bacteriophages in bacterial infections and the safety of phage therapy. Now, it…