Dr. Prasanth Manohar, Ph.D., – Page 34 – PHAGElogist

Next ‘Talk’ on Phage Therapy

Join me to know more about the problem of antibiotic resistance and the role of phage therapy in combating antibiotic resistance. Google Meet Link : https://meet.google.com/gxd-wqct-eht

SCIENCE: The microbiome and human cancer

The latest publication in Science(Vol. 371, Issue 6536, eabc4552, DOI: 10.1126/science.abc4552:) Separating microbes and cancers The role of microorganisms in causing and sustaining cancers has been in dispute for centuries.…

Microplastics in sewage supports the growth of drug-resistant bacteria

Ultra-fine plastic particles can become 'hubs' for antibiotic-resistant bacteria and pathogens to grow once they wash down household drains and enter wastewater treatment plants, a new study says. According to…

NIH awards $2.5 million for Bacteriophage therapy

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health, has awarded $2.5 million in grants to 12 institutes around the world to support…

Phage therapy on secondary Acinetobacter baumannii infection in COVID-19 patients

In this study, the authors describe the first therapeutic use of phages for the secondarybacterial infections in COVID-19 patients and the first clinical application of NEPT strategy to preview bacterial…

Mutations in metabolic genes can cause antibiotic resistance

A recent study in Science reveals a novel avenue by which genetic changes make bacteria resistant to drugs: mutations in genes involved in cellular metabolism, including some that convert food into energy. “The genes…

Bacteriophage uptake by mammalian cells

A very interesting study published in iScience titled "Bacteriophage uptake by mammalian cell layers represents a potential sink that may impact phage therapy". Source: https://www.cell.com/iscience/fulltext/S2589-0042(21)00255-8 Highlights Live-cell imaging showed that…

Interaction of bacteriophages with mammalian cells

Natural bacteriophages (present in the microbiome) and those applied as therapeutic agents may interact with mammalian cells and tissues. Adhesion interactions may define bacteriophage pharmacokinetics and resulting efficiency of bacteriophage…

Phage Therapy Successful in Mice, but Resistance Looms

Since just before the turn of the 20th century, bacteriophage’s antibacterial activity was detected in the waters of the Ganges and Yamuna rivers. English bacteriologist Ernest Hankin had written about the…

BiomX Inc. – Know about the phage company

BiomX Inc.: Clinical Stage Phage Therapeutics Company Looks Promising Summary BiomX is a clinical-stage microbiome company using its novel BOLT phage therapy platform to develop customized phage therapies to treat…