Dr. Prasanth Manohar, Ph.D., – Page 19 – PHAGElogist

Escape from phage infection by Gram-positive bacteria

A new article in Nature microbiology by Wohlfahrt et al. describes "L-form conversion in Gram-positive bacteria enables escape from phage infection" Abstract: At the end of a lytic bacteriophage replication…

BiomX reports “impressive” data in first bacteriophage trial

Hope that bacteriophages could represent a new therapeutic strategy for resistant bacterial infections has been bolstered by a study conducted by BiomX in cystic fibrosis (CF) patients. While still early,…

Phage Therapy in Germany-Latest

Phage Therapy in Germany—Update 2023 by Willy et al. Viruses 2023, 15(2), 588; https://doi.org/10.3390/v15020588 Abstract Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally and in Germany. Here, we provide an overview…

Bacteriophage endolysin powders for therapy

A new article punished in the International Journal of Pharmaceutics describes the "Bacteriophage endolysin powders for inhaled delivery against pulmonary infections" by Wang et al. https://doi.org/10.1016/j.ijpharm.2023.122679 Abstract Endolysins are bacteriophage-encoded…

Targeting Phage Therapy 2023

The 6th World Congress on Targeting Phage Therapy 2023 will take place on June 1-2 at IRIS, Paris, France. Targeting Phage 2023: Questions, Controversies, and What is Next? Targeting Phage…

Regulatory pathway needs to be developed to make the most of phages

A regulatory pathway needs to be developed if the UK is to reap the benefits of bacteriophage therapy, Applied Microbiology International (AMI) has warned. France, Belgium and Poland are already…

Publish in this special issue to communicate your phage research

A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Microbiology". Deadline for manuscript submissions: 12 May 2023 Special Issue "Bacteriophages: Infection, Genetics and Therapy" https://www.mdpi.com/journal/life/special_issues/196IPXRO2G Dear Colleagues, Bacteriophages…

The dynamic interplay of bacteriophage, bacteria and the mammalian host

Title: "The dynamic interplay of bacteriophage, bacteria and the mammalian host during phage therapy" AbstractFor decades, biomedically-centered studies of bacteria have focused on mechanistic drivers of disease in their mammalian…

Personalized Inhaled Bacteriophage Therapy Decreases MDR P. aeruginosa

In this fantastic work, Chan and colleagues show that using phage to treat P. aeruginosa lung infections in people with cystic fibrosis can lower P. aeruginosa levels, improve lung function, and drive…

PhageDiag project received grants from the EIC Accelerator Fund

Vésale Bioscience, a research and development company of solutions and treatments using phage therapy for multi-resistant infections, has announced it has received €1.8m (£1.6m) in grants from the European Innovation Council…