Dr. Prasanth Manohar, Ph.D., – Page 18 – PHAGElogist

Contaminated Eye Drops Outbreak; Bacteriophages maybe the Solution

CDC: Contaminated Eye Drops Outbreak Has Left 3 Dead, 4 With Eyeballs Removed The Pseudomonas aeruginosa outbreak linked to artificial tears has continued on its tear, so to speak. This is the…

Clinical data for oral phage therapy

BiomX Announces Positive Results of a Phase 1a Pharmacokinetic Study for Inflammatory Bowel Disease/Primary Sclerosing Cholangitis (IBD/PSC) Evaluating Delivery of Oral BX002 Phage Therapy BiomX has reported top-line findings from a phase…

Paris will host this year’s congress on “Targeting Phage Therapy”

Paris will host the 6th World Congress on Targeting Phage Therapy 2023 next June with more than 51 scientific communications from 27 different countries. More than 125 international academics and…

In the War on Bacteria, It’s Time to Call in the Phages

Researchers say viruses can kill antibiotic-resistant microbes and help treat infections. Regulators have to figure out how to get them on the market. ELLA BALASA WAS 26 when she realized the…

New Publication! Staph Phage

Phage-Antibiotic Combination: An Effective Method for Eradication of Staphylococcus aureus Archana Loganathan, Prasanth Manohar, Ramesh Nachimuthu https://www.biorxiv.org/content/10.1101/2023.03.27.534482v1 Abstract Increasing antibiotic resistance poses a serious threat, especially in patients admitted to…

Superbugs Flourish, Bacteriophage Therapy to Rescue

This NEW article in JAMA describes the current status of phage therapy clinical trials As Superbugs Flourish, Bacteriophage Therapy Recaptures Researchers’ Interest JAMA. 2023;329(10):781-784. doi:10.1001/jama.2022.17756 "Three weeks after the patient was…

Publication alert! “Phage Therapy”

The applications of animal models in phage therapy: An update Read here: https://doi.org/10.1080/21645515.2023.2175519 ABSTRACT The rapid increase in antibiotic resistance presents a dire situation necessitating the need for alternative therapeutic…

Bacteria killing too many people: Silent pandemic’ warning from WHO

World Health Organization (WHO) is warning of a 'silent pandemic' due to a lack of antibiotic development. The World Health Organization (WHO) is warning of a "silent pandemic" of antimicrobial resistance from…

The ‘Rapunzel’ virus: an evolutionary oddity

Extremely long tail provides window into how bacteria-infecting viruses assemble A recent study in the Journal of Biological Chemistry has revealed the secret behind an evolutionary marvel: a bacteriophage with an…

Phage cocktail, AP-PA02, safely lowers P. aeruginosa load

Potential efficacy also reported supports company plans for Phase 2b study AP-PA02, an experimental phage therapy for people with cystic fibrosis (CF) and chronic Pseudomonas aeruginosa respiratory infections, was well tolerated and reduced the bacterial load in…