Uncategorized World Antibiotic Awareness Week 2020 17 Nov 2020 Antibiotic Awareness Week, 18-24 November, 2020 WHO: World Antimicrobial Awareness Week (WAAW) aims to increase awareness of global antimicrobial resistance and to encourage best practices among the general public, health…
Uncategorized Locus Biosciences to develop K. pneumoniae-targeting phage therapy 11 Nov 2020 Locus Biosciences will develop its LBP-KP01, CRISPR-Cas3-enhanced bacteriophage product targeting Klebsiella pneumoniae with a $12.5 million partnership with the global nonprofit Combating Antibiotic-Resistant Bacteria Biopharmaceutical Accelerator (CARB-X). LBP-KP01 is a bacteriophage cocktail engineered…
Uncategorized Transfer of Antibiotic Resistance Genes from Gram-positive to Gram-negative Bacterium 7 Nov 2020 New Publication from my research group: Abstract The emergence of antibiotic resistance due to uncontrolled use of antibiotics in non-humans, poses a major threat for treating bacterial infections in humans.…
Uncategorized Drug-resistant superbug thriving in hospitals hit hard by COVID-19 6 Nov 2020 OVER CHRISTMAS BREAK in 2015, Johanna Rhodes received a panicked email from a doctor working at the Royal Brompton Hospital, the largest heart and lung center in the United Kingdom. A…
Uncategorized Clinical Trial of AP-PA02 Phage Therapy for P. aeruginosa Infections 1 Nov 2020 The U.S. Food and Drug Administration (FDA) cleared Armata Pharmaceuticals‘ investigational new drug (IND) application for a Phase 1b/2a clinical trial of AP-PA02 for the treatment of the Pseudomonas aeruginosa bacterial infections that are a hallmark of cystic fibrosis (CF). “We…
Uncategorized A Biological Inventory of Prophages in A. baumannii Genomes 31 Oct 2020 New publication from our lab, "A Biological Inventory of Prophages in A. baumannii Genomes Reveal Distinct Distributions in Classes, Length and Genomic Positions" authored by Belinda Loh, Jiayuan Chen, Prasanth Manohar, Yunsong Yu, Xiaoting Hua, Sebastian Leptihn Link: https://www.biorxiv.org/content/10.1101/2020.10.26.355222v1 Abstract Acinetobacter…
Uncategorized Phage Lab Finds Success with Hybrid Approach 28 Oct 2020 During what Kristen Butela, lecturer in the Department of Biological Sciences in the Kenneth P. Dietrich School of Arts and Sciences, half-jokingly refers to as “The Before Times,” her course-based undergraduate research class Foundations…
Uncategorized Phage Sensitivity Test in India 25 Oct 2020 In A First, Dr Dangs Lab Begins Bacteriophage Susceptibility Testing To Combat Antibiotic Resistance In an initiative that will enable thousands of Indians suffering from unresolved and antibiotic-resistant bacterial infections…
Uncategorized Antimicrobial resistance in South-East Asia 23 Oct 2020 Antimicrobial agents have played a critical role in reducing the burden of communicable diseases across the world. The WHO South-East Asia Region is no exception. Region-wide, antimicrobial drugs, including antibiotics,…
Uncategorized How pharma sector can contribute to contain the “Superbugs” menace in India 16 Oct 2020 ndia has one of the world’s highest number of bacterial infections; tuberculosis, cholera, typhoid, pneumonia and a host of them. In fact, the country has the highest number of tuberculosis patients…