Uncategorized Bacteriophage therapy and antibiotics to treat fracture-related infection 19 Jan 2022 A recently published article in Nature Communications shows that the combination of bacteriophages and antibiotics can treat K. pneumoniae fracture-related infections. Abstract A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella…
Uncategorized Benefits and Challenges Associated with Phage Therapy 14 Jan 2022 Dr Zemphira Alavidze, a medical microbiologist at Phage Therapy Center Phage Therapy Center was founded in 2003 by a leading group of Georgian microbiologists and polymer scientists. Their goal was to…
Uncategorized New animal model for phage research from our research team 7 Jan 2022 A multiwell-plate Caenorhabditis elegans assay for assessing the therapeutic potential of Bacteriophages against Clinical Pathogens Prasanth Manohar, Belinda Loh, Namasivayam Elangovan, Archana Loganathan, Ramesh Nachimuthu, Sebastian Leptihn Read the preprint here: https://www.biorxiv.org/content/10.1101/2022.01.05.474866v1 Abstract In order to establish phage therapy as a standard clinical…
Uncategorized New Publication in ACS Infectious Diseases 7 Jan 2022 Research: Synergistic Effects of Phage–Antibiotic Combinations against Citrobacter amalonaticus Authored by: Prasanth Manohar, Madhav Madurantakam Royam, Belinda Loh, Bulent Bozdogan, Ramesh Nachimuthu*, Sebastian Leptihn* Read full article here: https://pubs.acs.org/doi/10.1021/acsinfecdis.1c00117 Abstract Non-antibiotic…
Uncategorized The important role of prokaryotic viruses in sewage treatment uncovered 3 Jan 2022 Prokaryotic viruses (phages) existing in activated sludge (AS), a biological treatment process widely used in wastewater treatment plants (WWTPs), act to regulate the composition of the microbial community in the…
Uncategorized CDC launches networks to boost global response to antibiotic resistance 1 Jan 2022 The Centers for Disease Control and Prevention (CDC) announced a major initiative to bolster the global response to antimicrobial resistance (AMR). The CDC said it has awarded $22 million to 28 organizations in…
Uncategorized Immune and Genome Engineeringas the Future of Transplantable Tissue 24 Dec 2021 Published in "The New England Journal of Medicine" Tissue and organ failure that results from congenital abnormalities, trauma, disease, or aging contributes to substantial morbidity and mortality. Although the 20th…
Uncategorized New hiding place for antibiotic resistance 21 Dec 2021 University of Copenhagen researchers have shown that the prevailing assumption that resistant bacteria lose their resistance capability when antibiotics are not present is a truth requiring significant modifications. "One widespread…
Uncategorized Antibiotics overuse: “With resistance to 1st and 2nd line antibiotics, doctors forced to use reserve drugs” 13 Dec 2021 Sir Alexander Fleming in his Nobel lecture in 1945 said, “The time may come when penicillin can be bought by anyone in the shops. Then there is the danger that…
Uncategorized Formulating Bacteriophages 9 Dec 2021 What to consider when formulating bacteriophages? In this article, Dr Michael Koeris, Associate Professor, Bioprocessing at Keck Graduate Institute, and Carolina Moraes de Souza, Keck MEng graduate, now Process Development…