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Researchers say viruses can kill antibiotic-resistant microbes and help treat infections. Regulators have to figure out how to get them on the market. ELLA BALASA WAS 26 when she realized the…

Phage-Antibiotic Combination: An Effective Method for Eradication of Staphylococcus aureus Archana Loganathan, Prasanth Manohar, Ramesh Nachimuthu https://www.biorxiv.org/content/10.1101/2023.03.27.534482v1 Abstract Increasing antibiotic resistance poses a serious threat, especially in patients admitted to…

This NEW article in JAMA describes the current status of phage therapy clinical trials As Superbugs Flourish, Bacteriophage Therapy Recaptures Researchers’ Interest JAMA. 2023;329(10):781-784. doi:10.1001/jama.2022.17756 "Three weeks after the patient was…

The applications of animal models in phage therapy: An update Read here: https://doi.org/10.1080/21645515.2023.2175519 ABSTRACT The rapid increase in antibiotic resistance presents a dire situation necessitating the need for alternative therapeutic…

World Health Organization (WHO) is warning of a 'silent pandemic' due to a lack of antibiotic development. The World Health Organization (WHO) is warning of a "silent pandemic" of antimicrobial resistance from…

Extremely long tail provides window into how bacteria-infecting viruses assemble A recent study in the Journal of Biological Chemistry has revealed the secret behind an evolutionary marvel: a bacteriophage with an…

Potential efficacy also reported supports company plans for Phase 2b study AP-PA02, an experimental phage therapy for people with cystic fibrosis (CF) and chronic Pseudomonas aeruginosa respiratory infections, was well tolerated and reduced the bacterial load in…

A new article in Nature microbiology by Wohlfahrt et al. describes "L-form conversion in Gram-positive bacteria enables escape from phage infection" Abstract: At the end of a lytic bacteriophage replication…

Hope that bacteriophages could represent a new therapeutic strategy for resistant bacterial infections has been bolstered by a study conducted by BiomX in cystic fibrosis (CF) patients. While still early,…

Phage Therapy in Germany—Update 2023 by Willy et al. Viruses 2023, 15(2), 588; https://doi.org/10.3390/v15020588 Abstract Bacteriophage therapy holds promise in addressing the antibiotic-resistance crisis, globally and in Germany. Here, we provide an overview…