Uncategorized Phage-antibiotic combinations against P. aeruginosa biofilms 25 Oct 202311 Dec 2023 Phage-antibiotic combinations against multidrug-resistant Pseudomonas aeruginosa in in vitro static and dynamic biofilm models https://journals.asm.org/doi/pdf/10.1128/aac.00578-23 ABSTRACT: Biofilm-producing Pseudomonas aeruginosa infections pose a severe threat to public health and are responsible for high morbidity and mortality. Phage-antibi otic combinations (PACs)…
Uncategorized Bacteriophages in organic solvents 21 Oct 202311 Dec 2023 Stability of bacteriophages in organic solvents for formulations International Journal of Pharmaceutics, 2023 Abstract Bacteriophages or phages used as an alternative therapy for treating multi-drug resistant infections require formulation consideration.…
New: Single gene lysis proteins of ssRNA phages 18 Oct 20238 Dec 2023 Physiological characterization of single gene lysis proteins From Ry Young -Lysis lab Abstract Until recently only 11 distinct Sgls (single gene lysis proteins) have been experimentally identified. Of these, three…
Uncategorized Bacteriophages can increase the antibiotic sensitivity and immune response 8 Oct 2023 Recent article in the JOURNAL OF BACTERIOLOGY Bacteriophage steering of Burkholderia cenocepacia toward reduced virulence and increased antibiotic sensitivity ABSTRACT Antibiotic resistance in bacteria is a growing global concern and has spurred…
Uncategorized The clinical application of bacteriophages 3 Oct 2023 IN BMC Infectious Diseases: The World Health Organization (WHO) has indicated that the global new antibiotic discovery pipeline is inadequate to address the mounting threat of antimicrobial resistance (AMR) [1]…
Uncategorized The NOBLE Prize 2 Oct 2023 The 2023 Nobel Prize in Physiology or Medicine jointly to Katalin Karikó and Drew Weissman for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines…
Uncategorized New updates on ssRNA phages 28 Sep 2023 Recent Advances in Structural Studies of Single-Stranded RNA Bacteriophages Abstract Positive-sense single-stranded RNA (ssRNA) bacteriophages (phages) were first isolated six decades ago. Since then, extensive research has been conducted on…
Uncategorized Faecal transplantation and Phage-microbe dynamics 26 Sep 202326 Sep 2023 Phage-microbe dynamics after sterile faecal filtrate transplantation in individuals with metabolic syndrome: a double-blind, randomised, placebo-controlled clinical trial assessing efficacy and safety Abstract Bacteriophages (phages) are bacterial viruses that have…
Uncategorized Custom phage therapy for skincare 21 Sep 2023 No one likes to be reminded that their largest organ is a veritable menagerie of microbes. But Parallel Health turns the skin microbiome from creepy fact to potentially transformative skin care by engineering…
Uncategorized Phage Therapy: Research lacks basic phage-bacterial interaction 18 Sep 2023 Bacteriophage therapy: are we running before we have learned to walk? European Journal of Clinical Microbiology & Infectious Diseases (2023) Yet despite the paucity of research, the fervor for new antimicrobials…
