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More people seek bacteriophage therapy in Georgia Georgia hosts a unique scientific institute where bacteriophages—viruses that destroy bacterial cells—are studied. Bacteriophages (or simply “phages”) essentially serve as antibiotics. However, there’s still insufficient…

A new study published in Scientific Reports "An effective antibiofilm strategy based on bacteriophages armed with silver nanoparticles" shows the biofilms degrading potential of engineered bacteriophages armed with silver nanoparticles.…

A new study published in Viruses on "Lysis Physiology of Pseudomonas aeruginosa Infected with ssRNA Phage PRR1" https://www.mdpi.com/1999-4915/16/4/645 Abstract: The phage PRR1 belongs to the Leviviridae family, a group of ssRNA bacteriophages that infect…

Phage-antibiotic combinations to control Pseudomonas aeruginosa–Candida two-species biofilms https://www.nature.com/articles/s41598-024-59444-2 The use of phage-antibiotic combinations to treat bacterial infections is getting more attention. These combinations often have stronger effects when used together. However,…

Multi-Drug Resistant Bacteria Found on ISS Mutating to Become Functionally Distinct In a new scientific paper funded by an Ames Space Biology grant, Principal Investigator Dr. Kasthuri Venkateswaran of NASA’s…

A recent study shows the importance of immune response during phage administration. Phage-specific immunity impairs efficacy of bacteriophage targeting Vancomycin Resistant Enterococcus in a murine model Summary: In this study,…

Two latest papers (in Nature comm. and Science) from TAMU RNA phage group re-structured the ssRNA phage morphology with possible two "maturation/Mat" proteins, in and out. https://www.nature.com/articles/s41467-024-47119-5 https://www.science.org/doi/10.1126/science.adl0635

Phage-antibiotic combinations in various treatment modalities to manage MRSA infections The study explored the combined impact of the staph phage vB_Sau_S90 and four antibiotics on methicillin-resistant Staphylococcus aureus (MRSA). Three…

Physiological characterization of single-gene lysis proteins ABSTRACT Single-strand RNA (ssRNA) and single-strand DNA phages elicit host lysis using a single gene, in each case designated as sgl. Of the 11 identified…

Bacteriophages, also known as "phages," are viruses that naturally occur and only attack bacteria. They were discovered at the beginning of the century but were overshadowed by the focus on…