Dr. Prasanth Manohar, Ph.D., – Page 5 – PHAGElogist

First Use of Phage Therapy in Canada

First Use of Phage Therapy in Canada for the Treatment of a Life-Threatening, Multidrug-Resistant Staphylococcus epidermidis Periprosthetic Joint Infection: An N-of-1 Trial Abstract We describe the first use of phage therapy in…

Bacteriophage Therapy in Children

"Clinical Application of Bacteriophage Therapy in Children" Bacteriophages are highly specific in targeting single pathogens in the treat- ment of bacterial infections and thus offer a promising alternative to antibiotic…

New on Phage Therapy

Bacteriophage (phages) are viruses that exclusively use bacterial cells for propagation, killing the bacterial host in the process. In phage therapy, phages are used to reduce bacterial numbers, thereby curing…

phage ΦX174: Chloramphenicol and gentamicin reduce the evolution of resistance

Chloramphenicol and gentamicin reduce the evolution of resistance to phage ΦX174 by suppressing a subset of E. coli LPS mutants https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002952 Bacteriophages infect gram-negative bacteria by attaching to molecules present…

A flagella-dependent Burkholderia jumbo phage

Bacterial plant pathogens threaten many major food crops and inflict large agricultural losses worldwide. B. glumae is a bacterial plant pathogen that causes diseases such as rot, wilt, and blight in several…

Phage therapy: Phage Aussie survey

28 Jan 202528 Jan 2025

Policy in Practice: Cystic Fibrosis Australia and Phage Australia survey: understanding clinical needs and attitudes towards phage therapy in the CF community Cystic fibrosis (CF) is the most prevalent serious…

Award!

Mucosal-adapted bacteriophages

12 Jan 202512 Jan 2025

A new study published in Communications Biology "Mucosal-adapted bacteriophages as a preventive strategy for a lethal Pseudomonas aeruginosa challenge in mice" Abstract: Pseudomonas aeruginosa is an emergent threat due to the antimicrobial resistance…

Phage: Standardization of the Agar Plate Method

"Standardization of the Agar Plate Method for Bacteriophage Production" https://www.mdpi.com/2079-6382/14/1/2# Abstract The growing threat of antimicrobial resistance (AMR), exacerbated by the COVID-19 pandemic, highlights the urgent need for alternative treatments…

Develop an effective phage cocktail

A new study by Kim et al. "A blueprint for broadly effective bacteriophage-antibiotic cocktails against bacterial infections" Abstract Bacteriophage (phage) therapy is a promising therapeutic modality for multidrug-resistant bacterial infections,…