Dr. Prasanth Manohar, Ph.D., – Page 40 – PHAGElogist

Researchers Advance the Fight Against Antibiotic Resistance

Each year, about 2.8 million Americans get bacterial infections that resist treatment by the antibiotics designed to knock them out. About 35,000 of those patients die – globally the mortality…

Intravesical bacteriophages for treating urinary tract infections

Published in the Lancet Infectious Diseases Background Urinary tract infections (UTIs) are among the most prevalent microbial diseases and their financial burden on society is substantial. In the context of…

Bacteriophages could combat secondary COVID-19 infections

New research suggests that bacteriophage therapy could counteract the risk of secondary bacterial infections, which affect some patients with weakened immune systems after being infected with the SARS-CoV-2 coronavirus.A study…

Phage Therapy- Where are we now?

Phage therapy research in the West has accelerated in recent years. In practical terms, treatment options remain reserved for compassionate cases — but of the 29 such cases reported since…

Viral Fingerprints in Human Gut

Each person's gut virus composition is as unique as a fingerprint, according to the first study to assemble a comprehensive database of viral populations in the human digestive system. An…

One way to reverse antibiotic resistance in bacteria has now been found

Antibiotic resistance is a rising threat being faced by medical professionals all around the world If no solution to the problem is found, the estimate says millions of people will…

Standardized guidelines for phage therapy

When clinicians resort to phage therapy for patients who don't respond to antibiotics, the patients are usually very ill and time is of the essence. But the average time for…

Baby’s Meningitis Case Highlights Growing Danger of Antibiotic Resistance

Antibiotic-resistant bacteria affected the treatment of meningitis at a major children's hospital in Washington, D.C. This single case at Children's National Hospital raises concerns about drug resistance in the common…

Lysins Unlimited: Phages’ Secret Weapon

It was 1917 when Felix d’Herelle, at the Institut Pasteur in Paris, first proposed using bacteriophages (or phages)—viruses that infect bacteria—as a therapy for human bacterial infections. Although used for…

Bacteriophage purification for personalized phage therapy

Luong, T., Salabarria, A., Edwards, R.A. et al. Standardized bacteriophage purification for personalized phage therapy. Nat Protoc (2020). https://doi.org/10.1038/s41596-020-0346-0 The world is on the cusp of a post-antibiotic era, but researchers and medical doctors have…