Dr. Prasanth Manohar, Ph.D., – Page 4 – PHAGElogist

Sphae: To predict phage therapy candidates

A tool to identify suitable phage candidates for phage therapy. "Sphae: an automated toolkit for predicting phage therapy candidates from sequencing data" Abstract: The authors say "We developed Sphae, an…

Investigational Phage Therapy to treat Diabetic Foot Osteomyelitis

Investigational Phage Therapy Shows Positive Topline Results for Diabetic Foot Osteomyelitis Yesterday, an Israeli-based company, BiomX, announced results from its phase 2 trial studying its investigational phage therapy, BX211, which…

The Living Medicine

A new article, "The History of Phage Therapy", states: There are all kinds of reasons why the use of bacteriophages has failed to take off in the USA. “By the…

The International Association for Bacteriophage and AMR Research

Introducing a NEW association for researchers in the field of AMR and bacteriophages. I will be serving as a JOINT-SECRETARY. https://iabamrr.com The International Association for Bacteriophage and AMR (Antimicrobial Resistance)…

Phage: The deadliest beings on the planet

The deadliest beings on the planet: can the bacteriophage help in our fight against superbugs? Antimicrobial resistance threatens many of the gains of modern medicine, making even routine surgery much…

First Use of Phage Therapy in Canada

First Use of Phage Therapy in Canada for the Treatment of a Life-Threatening, Multidrug-Resistant Staphylococcus epidermidis Periprosthetic Joint Infection: An N-of-1 Trial Abstract We describe the first use of phage therapy in…

Bacteriophage Therapy in Children

"Clinical Application of Bacteriophage Therapy in Children" Bacteriophages are highly specific in targeting single pathogens in the treat- ment of bacterial infections and thus offer a promising alternative to antibiotic…

New on Phage Therapy

Bacteriophage (phages) are viruses that exclusively use bacterial cells for propagation, killing the bacterial host in the process. In phage therapy, phages are used to reduce bacterial numbers, thereby curing…

phage ΦX174: Chloramphenicol and gentamicin reduce the evolution of resistance

Chloramphenicol and gentamicin reduce the evolution of resistance to phage ΦX174 by suppressing a subset of E. coli LPS mutants https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002952 Bacteriophages infect gram-negative bacteria by attaching to molecules present…

A flagella-dependent Burkholderia jumbo phage

Bacterial plant pathogens threaten many major food crops and inflict large agricultural losses worldwide. B. glumae is a bacterial plant pathogen that causes diseases such as rot, wilt, and blight in several…