Dr. Prasanth Manohar, Ph.D., – Page 15 – PHAGElogist

Is it true? Picobirnaviruses are bacteriophages!

Recent interesting article published in PNAS questioned our previous understanding about the dsRNA virus, Picobirnaviridae. As a member of a lysis team (Ry Young group) it's interesting to evaluate these…

Need to fight: Superbugs are overpowering antibiotics

I have a clear memory of sitting on a Toronto-area park bench in 1985 as my dad—a computer executive and jack-of-all-trades—explained the arms race between our cells and a new…

Antibiotic resistance: How its started? and How its going?

Forbes: The Critical Fix We Need To Rebuild Our Broken Antibiotic Pipeline Recently, a Ukrainian soldier in his 50s suffered terrible burns in a vehicle fire. After he was transported…

Phages on filaments: Phage adsorption

Phages on filaments: A genetic screen elucidates the complex interactions between Salmonella enterica flagellin and bacteriophage Chi PLOS Pathogens, https://doi.org/10.1371/journal.ppat.1011537 Abstract The bacterial flagellum is a rotary motor organelle and important virulence…

Special Issue “Call for papers – Bacterial defense systems”

BMC Microbiology welcomes submissions to a collection on ‘Bacterial defense systems’. Through this collection, we acknowledge that research on bacterial defense mechanisms, as well as their potential applications, is rapidly evolving…

Human Neutrophil Response to Phages

Human Neutrophil Response to Pseudomonas Bacteriophage PAK_P1, a Therapeutic Candidate Viruses 2023, 15(8), 1726; https://doi.org/10.3390/v15081726 Abstract The immune system offers several mechanisms of response to harmful microbes that invade the human body. As a first…

Phage therapy shows promise in treating Pseudomonas aeruginosa infections

A new international study conducted by the Israeli Phage Therapy Center (IPTC) led by Prof. Ran Nir-Paz at Hadassah Hebrew University Medical Center and Prof. Ronen Hazan of the Faculty…

Phages, a good virus can beat bacteria that resist antibiotics

The study paves the way for future clinical trials and encourages further exploration of phage therapy as an alternative and auxiliary approach against antibiotic-resistant infections. The growing resistance of bacteria…

‘The Good Virus’- Book to read

8 Aug 20238 Aug 2023

The Good Virus review: Could viruses cure deadly infections? Tom Ireland's compelling and original book makes a strong case for revisiting phage therapy – the idea of fighting bacterial infections…

Cystic Fibrosis: Bacteriophage Therapy for PDR Pseudomonas aeruginosa

Case Report A 6-year-old African American female (Pt1) and 26-year-old Hispanic female (Pt2) patients, both with CF, respiratory cultures positive for MDR P. aeruginosa, and advanced lung disease, were treated with…