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Author: Dr. Prasanth Manohar, Ph.D.,

Early career researcher in the field of Microbiology. Phage biologist, Author, Editor and Scientific writer. Expertise is in bacteriophage biology & genetics, Phage Therapy, ssRNA phages, Phage lysis systems, Single-cell analysis, protein antibiotics, and Antibiotic Resistance.
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When Antibiotics Fail: Need for Phage Therapy

11 May 202411 May 2024
More people seek bacteriophage therapy in Georgia Georgia hosts a unique scientific institute where bacteriophages—viruses that destroy bacterial cells—are studied. Bacteriophages (or simply “phages”) essentially serve as antibiotics. However, there’s still insufficient…
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Bacteriophages armed with silver nanoparticles

29 Apr 202429 Apr 2024
A new study published in Scientific Reports "An effective antibiofilm strategy based on bacteriophages armed with silver nanoparticles" shows the biofilms degrading potential of engineered bacteriophages armed with silver nanoparticles.…
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Lysis: Pseudomonas aeruginosa Infected with ssRNA

25 Apr 202429 Apr 2024
A new study published in Viruses on "Lysis Physiology of Pseudomonas aeruginosa Infected with ssRNA Phage PRR1" https://www.mdpi.com/1999-4915/16/4/645 Abstract: The phage PRR1 belongs to the Leviviridae family, a group of ssRNA bacteriophages that infect…
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New Publication! Phage-antifungal Combination against dual-species biofilms

24 Apr 202424 Apr 2024
Phage-antibiotic combinations to control Pseudomonas aeruginosa–Candida two-species biofilms https://www.nature.com/articles/s41598-024-59444-2 The use of phage-antibiotic combinations to treat bacterial infections is getting more attention. These combinations often have stronger effects when used together. However,…
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Multi-drug resistant bacteria in space

20 Apr 202420 Apr 2024
Multi-Drug Resistant Bacteria Found on ISS Mutating to Become Functionally Distinct In a new scientific paper funded by an Ames Space Biology grant, Principal Investigator Dr. Kasthuri Venkateswaran of NASA’s…
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Phage-specific immunity and treatment

8 Apr 20248 Apr 2024
A recent study shows the importance of immune response during phage administration. Phage-specific immunity impairs efficacy of bacteriophage targeting Vancomycin Resistant Enterococcus in a murine model Summary: In this study,…
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New shape to RNA phage structure

5 Apr 20245 Apr 2024
Two latest papers (in Nature comm. and Science) from TAMU RNA phage group re-structured the ssRNA phage morphology with possible two "maturation/Mat" proteins, in and out. https://www.nature.com/articles/s41467-024-47119-5 https://www.science.org/doi/10.1126/science.adl0635
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New Publication: Phage-antibiotic combinations

23 Mar 20248 Apr 2024
Phage-antibiotic combinations in various treatment modalities to manage MRSA infections The study explored the combined impact of the staph phage vB_Sau_S90 and four antibiotics on methicillin-resistant Staphylococcus aureus (MRSA). Three…
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Future antibiotics: Single gene lysis proteins

22 Mar 202422 Mar 2024
Physiological characterization of single-gene lysis proteins ABSTRACT Single-strand RNA (ssRNA) and single-strand DNA phages elicit host lysis using a single gene, in each case designated as sgl. Of the 11 identified…
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Forbes: Phages, The Next Trillion Dollar Idea In Biotech

13 Mar 202413 Mar 2024
Bacteriophages, also known as "phages," are viruses that naturally occur and only attack bacteria. They were discovered at the beginning of the century but were overshadowed by the focus on…

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Dr. Prasanth Manohar, PhD
Staff Scientist,
Biochemistry and Biology, HMU Health and Medical University, Erfurt, Germany. Plaußiger Straße 9, 04318 Leipzig

Reach me:
Mobile:
+49 (0)162 5326812
+91-96005 08051

E-mail:
prasanth.phage@gmail.com
prasanth.manohar@hmu-erfurt.de
prasanthmanohar.phd@gmail.com

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