Uncategorized Discovered a new type of holin(s)-Lysis lab 30 Aug 202430 Aug 2024 Publication coming soon... Holins As a part of the lytic system of dsDNA phages, holins play two fundamental roles: they create holes in the inner membrane for the release of the endolysins, and determine the…
Uncategorized Antibacterial effect of phage cocktails and phage-antibiotic synergy 24 Aug 202424 Aug 2024 A new study "Antibacterial effect of phage cocktails and phage-antibiotic synergy against pathogenic Klebsiella pneumoniae" https://journals.asm.org/doi/full/10.1128/msystems.00607-24 ABSTRACT The global rise of antibiotic resistance has renewed interest in phage therapy, as an…
Uncategorized Safety, pharmacokinetics, and pharmacodynamics of LBP-EC01, a CRISPR-Cas3-enhanced bacteriophage cocktail 14 Aug 202414 Aug 2024 Safety, pharmacokinetics, and pharmacodynamics of LBP-EC01, a CRISPR-Cas3-enhanced bacteriophage cocktail, in uncomplicated urinary tract infections due to Escherichia coli (ELIMINATE): the randomised, open-label, first part of a two-part phase 2 trial DOI:https://doi.org/10.1016/S1473-3099(24)00424-9…
Uncategorized A new model to study the combination of antibiotics with a bacteriophage cocktail 9 Aug 20249 Aug 2024 Bacteriophages as potential antibiotic potentiators in cystic fibrosis: A new model to study the combination of antibiotics with a bacteriophage cocktail targeting dual species biofilms of Staphylococcus aureusand Pseudomonas aeruginosa International Journal…
Uncategorized Microbiome: the leading companies in bacteriophage therapy 4 Aug 20244 Aug 2024 The pharmaceutical industry continues to be a hotbed of patent innovation. Activity is driven by the evolution of treatment paradigms, and the gravity of unmet needs, as well as the…
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