January 2023 – PHAGElogist

The dynamic interplay of bacteriophage, bacteria and the mammalian host

Title: "The dynamic interplay of bacteriophage, bacteria and the mammalian host during phage therapy" AbstractFor decades, biomedically-centered studies of bacteria have focused on mechanistic drivers of disease in their mammalian…

Personalized Inhaled Bacteriophage Therapy Decreases MDR P. aeruginosa

In this fantastic work, Chan and colleagues show that using phage to treat P. aeruginosa lung infections in people with cystic fibrosis can lower P. aeruginosa levels, improve lung function, and drive…

PhageDiag project received grants from the EIC Accelerator Fund

Vésale Bioscience, a research and development company of solutions and treatments using phage therapy for multi-resistant infections, has announced it has received €1.8m (£1.6m) in grants from the European Innovation Council…

First-in-human application of double-stranded RNA bacteriophage

Publication: Brief Report - "First-in-human application of double-stranded RNA bacteriophage in the treatment of pulmonary Pseudomonas aeruginosa infection" by Li et al. https://doi.org/10.1111/1751-7915.14217 Abstract A double-stranded RNA (dsRNA) phage phiYY is able…

Adaptive Phage Therapeutics Announces First Patient Dosed in the PHAGE Clinical Trial

Adaptive Phage Therapeutics, Inc., (APT) a clinical-stage biotechnology company advancing the APT phage bank, the world’s largest therapeutic phage initiative for treatment of bacterial infectious diseases, today announced the first…

Are bacteriophages the new antibiotics?

Bacteriophages, viruses that infect bacteria, may be used as an alternative treatment option when antibiotics fail. Leiden researchers have studied the structure and function of a novel bacteriophage that could…

New Year; New Role; New Beginning…

Excited!!! Starting a new position as a "Postdoctoral Research Associate" (in NIH project) at the Center for Phage Technology (Young lab), Department of Biochemistry and Biophysics, Texas A&M AgriLife Research,…