October 2022 – PHAGElogist

Diagnostics, drug resistance and commitment to combat AMR

Fuelled by the misuse and overuse of antibiotics, researchers believe that antimicrobial resistance could ultimately take more than 10 million lives per year by 2050. While the burden is universal,…

World Phage Week

Let's celebrate "WORLD Phage Week" - Oct 22-28, 2022. #phagologist #phagetherapy Bacteriophages (or phages) are bacteria infecting/ killing viruses. Phages are used to cure bacterial infections.

The war in Ukraine is fueling antimicrobial resistance

The war in Ukraine is increasing the spread of antimicrobial resistance, said Dr. Laura Jung, a clinician and researcher on antibiotic resistance at the University of Leipzig Medical Center in Germany,…

Gonorrhea became more drug resistant while attention was on COVID-19

COVID-19 has rightfully dominated infectious disease news since 2020. However, that doesn’t mean other infectious diseases took a break. In fact, U.S. rates of infection by gonorrhea have risen during the…

Phage Therapy Market Size in 2022 – 2028

“Phage Therapy” Market Insights | No of Pages120| By Application [Animal Health, Aquaculture, Agriculture, Food Industry, Human Health, Others], By Type [DsDNA Bacteriophage, ssDNA Bacteriophage, ssRNA Bacteriophage, Others]. The Phage…

New Publication!

In vitro and in vivo evaluation of the biofilm-degrading Pseudomonasphage Motto, as a candidate for phage therapy Prasanth Manohar, Belinda Loh, Dann Turner, Tamizhselvi Ramasamy, Marimuthu Mathankumar, Namasivayam Elangovan, Ramesh Nachimuthu, Sebastian Leptihn https://www.biorxiv.org/content/10.1101/2022.10.12.512010v1 Abstract Infections caused by Pseudomonas aeruginosa are becoming increasingly difficult to treat due to the emergence…

New Publication! Phage Genome

Complete Genome Sequence of Pseudomonas Phage Motto Authors: Prasanth Manohar, Archana Loganathan, Ramesh Nachimuthu, Belinda Loh, Long Ma, Dann Turner, Sebastian Leptihn ABSTRACT We describe the complete genome sequence of bacteriophage Motto, which infects clinical strains of Pseudomonas aeruginosa. Motto is a T1-like siphovirus related to members…

Host Immunity to Phage Therapy

In a lung transplant recipient, phage therapy was associated with a T follicular helper cell response and production of neutralizing antibody. Phage therapy with bacteriophages (viruses that infect bacteria) has…

NIH-supported clinical trial of phage therapy for cystic fibrosis

Enrollment has begun in an early-stage clinical trial evaluating bacteriophage therapy in adults with cystic fibrosis (CF) who carry Pseudomonas aeruginosa (P. aeruginosa) in their lungs. The trial is evaluating whether…

Bacteriophage-antibiotic combination therapy saves a young boy

Bacteriophage-antibiotic combination therapy against extensively drug-resistant Pseudomonas aeruginosainfection to allow liver transplantation in a toddler Nature Communications volume 13, Article number: 5725 (2022) Read here: https://www.nature.com/articles/s41467-022-33294-w