January 2022 – PHAGElogist

The World’s Next Big Health Emergency Is Already Here

Covid-19 has claimed nearly 6 million lives. Antimicrobial resistance may claim 10 million annually by 2050 — and that figure is starting to look low. If we look on the bright side of the past…

Special Phage Therapy Clears a Patient’s Resistant Infection After 798 Days

After 700 days of antibiotic treatment, the infection of a 30-year-old bombing attack victim still raged. Tragically, the patient had suffered life-threatening injuries during the attacks at Brussels airport on 22…

Bacteriophage therapy and antibiotics to treat fracture-related infection

A recently published article in Nature Communications shows that the combination of bacteriophages and antibiotics can treat K. pneumoniae fracture-related infections. Abstract A 30-year-old bombing victim with a fracture-related pandrug-resistant Klebsiella…

Benefits and Challenges Associated with Phage Therapy

Dr Zemphira Alavidze, a medical microbiologist at Phage Therapy Center Phage Therapy Center was founded in 2003 by a leading group of Georgian microbiologists and polymer scientists. Their goal was to…

New animal model for phage research from our research team

A multiwell-plate Caenorhabditis elegans assay for assessing the therapeutic potential of Bacteriophages against Clinical Pathogens Prasanth Manohar, Belinda Loh, Namasivayam Elangovan, Archana Loganathan, Ramesh Nachimuthu, Sebastian Leptihn Read the preprint here: https://www.biorxiv.org/content/10.1101/2022.01.05.474866v1 Abstract In order to establish phage therapy as a standard clinical…

New Publication in ACS Infectious Diseases

Research: Synergistic Effects of Phage–Antibiotic Combinations against Citrobacter amalonaticus Authored by: Prasanth Manohar, Madhav Madurantakam Royam, Belinda Loh, Bulent Bozdogan, Ramesh Nachimuthu*, Sebastian Leptihn* Read full article here: https://pubs.acs.org/doi/10.1021/acsinfecdis.1c00117 Abstract Non-antibiotic…

The important role of prokaryotic viruses in sewage treatment uncovered

Prokaryotic viruses (phages) existing in activated sludge (AS), a biological treatment process widely used in wastewater treatment plants (WWTPs), act to regulate the composition of the microbial community in the…

CDC launches networks to boost global response to antibiotic resistance

The Centers for Disease Control and Prevention (CDC) announced a major initiative to bolster the global response to antimicrobial resistance (AMR). The CDC said it has awarded $22 million to 28 organizations in…